Type+1+Diabetes

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=Type 1 DIABETES = = = = = = = = = = = = = = = = = = = = = =Introduction=

"Diabetes mellitus" is a group of metabolic diseases characterized by high blood sugar levels, which result from defects in insulin secretion. Diabetes mellitus, commonly referred to as diabetes. TYPE 1 DIABETES, is typically, however, not exclusively diagnosed in children and young adults. It is also known as "juvenile diabetes". When you have TYPE 1 DIABETES, your body does not produce insulin, which is a hormone that is needed to convert starches and sugars into energy. This usually is as a result of an Auto Immune disease where the immune system attacks the beta cells in the pancreas that produce insulin. Without regulation fluctuating blood sugar levels can lead serious problems like Hypoglycemia (dangerously low levels of blood sugars), Hyperglycemia (dangerously high levels of blood sugars), and Ketoacidosis which is a condition where your blood contains dangerously high levels of Ketones, which can result in a diabetic coma and even death.

There is no known cause for diabetes and there are no known preventative measures. People with TYPE 1 DIABETES must undergo daily insulin injections. Though the condition is severe it is not life threatening if controlled and monitored. The only known cure for DIABETES is a pancreatic transplant, which isn't always successful.

=Type 1 Diabetes on a molecular Level=

Diabetes is a multifactorial condition characterized by the autoimmune destruction of insulin (C258H384N64O78S6) secreting Beta Cells in the pancreas.The destructive process leads to severe insulin depletion, which results in hyperglycemia, because of hepatic overproduction of glucose (C6H12O6) glycogenolysis and gluconeogenesis and decreased cellular uptake of glucose. In absence of insulin there is also an increased breakdown of fat and fatty acid oxidation, resulting in excessive Ketone production, which in turn can lead to Ketoacidosis.

For more information visit these sites:
[|Type 1 Diabetes] http://www.endocrineweb.com/diabetes/1diabetes.html =Works Cited= = = http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1187280 http://www.diabetes.org/type-1-diabetes.jsp http://en.wikipedia.org/wiki/Diabetes_mellitus_type_1

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