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=__Celiac Disease__= By: Zack Schibner

What is the Celiac Disease?
The Celiac Disease is a digestive disease, which damages the small intestine and it interferes with the absorption of food and nutrients. The people who have this disease cannot have anything to deal with glutten, a protein that has wheat, rye or barley. If a person with this disease eats anything like barley, wheat, glutten or barley then their immune system does not allow it by destroying the insides, which is the Villi. The Villi is a tiny fingerlike protrusions lining the small intestines. Villi allows the nutrients from the food to be able to go through the walls of the small intestine. Without those healty Villis then there will be not enough nutrients getting through and the person will start to become malnourished.

Symptoms for a Child/Infant:

 * Abdominal bloating and pain
 * Chronic Diarrhea
 * Vomiting
 * Constipation
 * Pale, Foul-Smelling and Fatty Stool
 * Weight Loss

Symptoms for an Adult:

 * Iron-deficiency anemia
 * Fatigue
 * Bone or joint pain
 * Arthritis
 * Bone loss or osteoporosis
 * Depression or anxiety
 * Seizures
 * Tingling numbness in hands and feet
 * Missed menstral periods
 * Skin rash called dermatitis herpitiformis
 * Canker sores inside the mouth

Recognizing Celiac Disease
Because of the symptoms that this disease has it is harder to recognize whether someone has it or not. Doctors have trouble recognizing this disease. Different ways of how they diagnose the Celiac Disease are Blood Tests, Intestinal Biopsy, Dermatitiis Herpitiformis, and Screening. Once they find out if that person has the disease then there is only one way to treat something like that. It is a Glutten-Free Diet.

Mutated/Non-Mutated Gene
There are two different people. People who have this disease and people who do not have this disease in this situation. The people who have this disease there are symptoms (which are listed above) that can happen to the people who have this disease. There are different symtpoms that can happen to either the adults and the children. Then the people who do not have this disease are just normal people and nothing will happen to them like the stuff that might happen to the people with this disease. The people who do not have this disease are just going to live their life as normal as possible.

Gene Regions
In the body there are 7 gene regions where they cause the Celiac Disease. The scientists who examined this were David Van Heel, who was the leader who lead this investigation.

Gene/Gene Location
This disease is located in the gene HLA-DQB1. This gene is located on the 6th chromosome. This gene is a human gene which denotes the genetic locus which contains the actual gene. This picture below is the location of the gene HLA-DQB1.



Celiac Disease
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