Fredrich's+Disease

=toc Introduction= Friedrich disease, according to Claude St-Jean Foundation, "is an autosomal recessive inherited disease that causes progressive damage to the nervous system. It manifests in the initial symptoms of poor coordination such as gait disturbance, it can also lead to scoliosis, heart disease and diabetes, but does not affect cognitive function." This disease is also known as Friedrich Ataxia, but is not a vey common disease. =Molecular Basis= It is a disease that effects a large amount of organs and tissue with the loss of sensory neutrons and life threatening and can cause cardiac arrest or a disease known as HCM at its most severe manifestations. Limited amounts of iron stored in the Frataxin can lead to cell- damaging oxidation stress and FDRA is considered as a model for more common diseases that affect the neurons in the brain known as Neurodegenerative diseases. media type="youtube" key="ThMH3WCUU4A" width="560" height="315"