Amoxicillin



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Properties

Molar Mass - 350.3 moles
Formula - C16H19N3O5S.3H2O
Density - .320 g/mL
Melting Point - 194 C
Boiling Point - 743.2 C
Solubility - 3430 mg/L
IUPAC Name - (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2 carboxylic acid
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Structure

Percent Composition by mass:

Carbon - 55%
Hydrogen - 55%
Nitrogen - 12%
Oxygen - 23%
Sodium - 92%

Hydrogen - 11%
Oxygen - 88%

Percent Composition by number:

Carbon - 36.36%
Hydrogen - 43.18%
Nitrogen - 6.82%
Oxygen - 11.36%
Sodium - 2.27%

Hydrogen - 66.66%
Oxygen - 33.33%

Bonding Type: Covalent Bond


Uses and Reactions

Amoxicillin is also a penicillin, it is used commonly as an antibiotic. Amoxicillin is prescribed for patients with a bacterial infections such as streptococcal pharyngitist . Usually used for infections in the ear, nose, or throat. It can be in a liquid or solid state and is taken orally. Unfortunately, taking this amoxicillin or ampillicin can cause a non-allergic reaction, known as the amoxicillin rash. Also, some common side effects are mood swings, dizziness, vomiting, fatigue and much more
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History

Penicillin was made for human use in 1943 by Alexander Fleming, Ernst Chain and Howard Florey. This new discovery helped save many lives especially during World War II. Although, Penicillin improved the lives of many people, there's always room for improvement. Penicillin didn't last very long and didn't proctect the body from all the infected bacteria. Amoxicillin was this new demand of many patients with the bacterial infections.


Found

Amoxicillin comes from penicillin. Penicillin originates from Penicillium mold. Penicillium mold grows in soil, dieing plants, rotten fruits, and other dried foods. Amoxicillin and Penicillin are antibotics, which are forms of bacteria and fungi.


Chemical Properties

Amoxicillin is a Trihydrate and is stable but imcompatible with strong oxidizing agents.

3-D Model




Resources

Info

"List of Organic Compounds". wikipedia. 11/19/09 http://en.wikipedia.org/wiki/List_of_organic_compounds
"Ampicillin". wikipedia. 11/19/09 http://en.wikipedia.org/wiki/Ampicillin
"Amoxicillin". wikipedia. 11/19/09 http://en.wikipedia.org/wiki/Amoxicillin.
"Amoxicillin Sodium". look chem. 11/19/09 http://www.lookchem.com/cas-346/34642-77-8.html
"Showing Card for Amoxicillin". Drug Bank. 11/19/09 http://www.drugbank.ca/drugs/DB01060
"Penicillin sp, ". Mold Library . 11/19/09 http://www.environix.com/what-is-IAQ/library-mold/Penicillium/
Bellis, Mary. "The History of Penicillin". About.com. 11/19/09 http://inventors.about.com/od/pstartinventions/a/Penicillin.htm
"Amoxicillin". History and Background. 11/19/09 http://inventors.about.com/od/pstartinventions/a/Penicillin.htm
"Amoxicillin". PharmGKb. 11/19/09 http://www.pharmgkb.org/views/index.jsp?objId=PA448406
"Amoxicillin Product Description". Chemical Book. 11/19/09 http://www.chemicalbook.com/ChemicalProductProperty_EN_CB3690305.htm




Pictures

http://search.creativecommons.org/#
http://en.academic.ru/pictures/enwiki/65/Amoxicillin-2D-skeletal.png
http://upload.wikimedia.org/wikipedia/commons/a/ac/Amoxicillin_rash_11_hours_after_17th_dose.JPG

JMOL 3D Model

"Amoxicillin Chemical Book". Chemical Book. 11/24/09 http://www.chemicalbook.com/Search_EN.aspx?keyword=amoxicillin


By: Alicia