Acetaminophenkpeairs



(Mac users please save this file and open with iMol. You can download that from iMol's website)



external image Extra_Strength_Tylenol_and_Tylenol_PM.jpgexternal image Paracetamol_acetaminophen_500_mg_pills_crop.jpg

Chemical Properties:
1. Chemical Formula:
  • C8H9NO2
2. Molar Mass:
  • 151.16256
3. Melting point:
  • 169 - 172 C
4. Density:
  • 1.263 g/cm³
5. Boiling Point
  • Acetaminophen does not have a boiling point. (instead of boil it desintegrates)
6. Mass Percent Composition
  • 75.69% C
  • 8.80%H
  • 15.51% O
7. Percent number composition
C- 40
H- 45
O- 10


8. Reaction Tendencies:
Acetaminop



external image 461725203_5bcf52de28.jpg


Structure:
The core is made up of a benzene ring, and also contains a hydroxyl group. The ring is highly reactive but all positions on the ring are pretty well filled.

external image ACETAMINOPHEN_PARACETAMOL.summ.jpg


History:

First used as a pain reliever in the early 1800s, Acetaminophen first began its distribution in the early 1950s after being approved by the U.S. Food and Drug Administration. Acetaminophen was very safe to be used by children or those who suffer from ulcers. The chemical name of acetaminophen is 4-hydroxyacetanalide Today, the most common brand that uses acetaminophen would be Tylenol. In 1955 Tylenol included the chemical in Childrens' Tylenol in 500 mg tablets, safe for moderate consumption for pain relief. The drug is not actually toxic but N-acetyl- p -benzoquinonimine is formed when the drug breaks down. Originally, the only way acetaminophen could be acquired was by prescription for the relief of pain and fever. Currently Tylenol is one of the top selling brands of pain relief in the united states. Can be used to treat chronic and acute pain and is considered more potent than other prescription drugs. Acetaminophen is a main ingredient in many cold medications as well. Over consumption of Acetaminophen can lead to liver failure like many other medications. Acetaminophen causes less stomach irritation and blood clots than leading brands of medication such as Aspirins.

Where it's found:
Harmon Northrop Morse created Acetaminophen by reducing p-nitrophenol with tin in a substance called glacial acetic acid. He first did this in 1873 but it wasn't produced medically for another twenty years. Acetaminophen was located in the urine of people who had taken phenacetin and the substance was reduced to a white powder that was bitter tasting.


Uses:
Acetaminophen is a pain reliever and fever reducer and can be found in some over-the-counter medications such as Tylenol and Excedrin.


important links:

"ACETAMINOPHEN (PARACETAMOL)." Worldwide Chemical Information, Trading & Advertising. Web. 27 Oct. 2010. http://www.chemicalland21.com/lifescience/phar/ACETAMINOPHEN.htm.

"Acetaminophen Summary | BookRags.com." BookRags.com | Study Guides, Lesson Plans, Book Summaries and More. Web. 27 Oct. 2010. http://www.bookrags.com/research/acetaminophen-chmc/.

"Molecular Weight of Acetaminophen." Convert Units - Measurement Unit Converter. Web. 27 Oct. 2010. http://www.convertunits.com/molarmass/Acetaminophen.

"Paracetamol." Wikipedia, the Free Encyclopedia. Web. 27 Oct. 2010. http://en.wikipedia.org/wiki/Paracetamol.

Photograph. Web. <"ACETAMINOPHEN (PARACETAMOL)." Worldwide Chemical Information, Trading & Advertising. Web. 27 Oct. 2010. .>.

Photograph. Web. http://farm1.static.flickr.com/187/461725203_5bcf52de28.jpg.

Photograph. Web. http://i00.i.aliimg.com/photo/v0/107082438/ACETAMINOPHEN_PARACETAMOL.summ.jpg.

Photograph. Web. http://upload.wikimedia.org/wikipedia/commons/f/f8/Paracetamol_acetaminophen_500_mg_pills_crop.jpg.