Aspirin

external image Aspirin-007.jpg



General information-

IUPAC name- 2-acetoxybenzoic acid
external image image.png?cmp=2-acetoxybenzoic_acid

Molar mass- 180.157 g/mol
Formula name- C9H8O4
Melting point- 136* C
Boiling point- 140* C
Density- 1.40 g/cm3


Background-

In 1763, Edward Stone isolated the active ingredient of aspirin in his discovery of salicylic acid. In 1853 a french chemist named, Charles Frederic Gerhardt, was the first person to prepare acetysalicylic acid. He eventually mixed it with acetyl chloride with a sodium salt, and a vigorous reaction. Later many people experimented with it and got the same results, pure acetylsalicylic acid. In 1897 chemists at Bayer made a synthetic version of the real pure acetylsalicylic acid that was less harsh on your stomach. It was now named aspirin.


Where is it found?-

It is found without a prescription on store shelves.

Uses-

It is used to treat many things including acute pain, fevers, rheumatic fever and inflammatory diseases such as rheumatoid arthritis. Aspirin has also been shown to greatly reduce the risk of a heart attack or the risk of stroke in some cases.

References-

http://en.wikipedia.org/wiki/Aspirin
https://www.google.com/#q=aspirin
Pictures-
http://www.techtimes.com/articles/9261/20140626/a-little-aspirin-may-help-ward-off-pancreatic-cancer.htm
http://wtt-pro.nist.gov/wtt-pro/index.html?cmp=2-acetoxybenzoic_acid


Inserting a Chime file


For Windows:


  1. Install the MDL Chime plug-in
  2. Download a Chime file (.pdb)
  3. Upload your file
  4. Add Widget, Other HTML
  5. Paste in the following code: (be sure to change the "yourfilename.pdb" part to your actual file name)

<embed src="http://cornellbiochem.wikispaces.com/space/showimage/yourfilename.pdb" align="baseline" border="2" width="160" height="160" display3d="ball&amp;stick" options3d="specular" startspin="true" spiny="180" spinz="180" color3d="cpk" />

For Mac:


  1. Upload your .pdb or .mol file and add to your page as an attachment.
  2. Direct users to save the file and open with iMol.